Before full cosmid prep, PCR is used to screen pooled clones. A typical shows:
The cosmid pic is not just documentation; it’s a diagnostic tool. cosmid pics
These schematic pics allow researchers to plan their cloning strategy. If the map shows a unique BamHI site inside the cos site, you know that opening the cosmid with that enzyme will linearize it for ligation to your insert. Cosmid Pics: A Visual Odyssey Part 3: Gel
Usually an antibiotic resistance gene. This allows scientists to identify which bacteria have successfully taken up the cosmid. cosmid pics